Amelogenins as Potential Buffers during Secretory-stage Amelogenesis
نویسندگان
چکیده
منابع مشابه
Co-operative mineralization and protein self-assembly in amelogenesis: silica mineralization and assembly of recombinant amelogenins in vitro.
An amorphous silica mineralization technique was used to produce inorganic/protein composites to elucidate the structure and mechanism of formation of amelogenin assemblies, which may play an important role in regulating enamel structure during the initial stages of amelogenesis. Full-length recombinant amelogenins from mouse (rM179) and pig (rP172) were investigated along with key degradation ...
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Introduction Administration of fluoride is known to induce various ultrastructural changes in secretory ameloblasts1-9). One characteristic change occurring in cells is the appearance of globular bodies and large vacuoles that probably originate in secretion granules or the endoplasmic reticulum1-3,8). The true origin of these bodies or vacuoles, however, will remain unsettled until their chemi...
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متن کاملThe enamel protein amelogenin binds to the N-acetyl-D-glucosamine-mimicking peptide motif of cytokeratins.
Amelogenins bind to GlcNAc of the dentine-enamel matrix proteins (Ravindranath, R. M. H., Moradian-Oldak, J., Fincham, A. G. (1999) J. Biol. Chem. 274, 2464-2471). The hypothesis that amelogenins may interact with the peptides that mimic GlcNAc is tested. GlcNAc-mimicking peptide (SFGSGFGGGY) but not its variants with single amino acid substitution at serine, tyrosine, or phenylalanine residues...
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ژورنال
عنوان ژورنال: Journal of Dental Research
سال: 2014
ISSN: 0022-0345,1544-0591
DOI: 10.1177/0022034514564186